Exploring the risk of glycemic variability in non-diabetic depressive individuals: a cross-sectional GlyDep pilot study

Background Data on the correlation between glycemic variability and depression in nondiabetic patients remain limited. Considering link increased cardiovascular risks, this relationship could be significant depressed patients. Methods In single-center pilot study, we utilized Flash Glucose Monitoring (Abbott Libre Pro) to study variability. The CES-D (Center for Epidemiological Studies– Depression) scale was employed measure levels. Based scores, were classified into two groups: those with scores ≥ 33 < 33. We analyzed various indices, including HBGI, CONGA, ADDR, MAGE, MAG, LI, J-Index, employing EasyGV version 9.0 software. SPSS (version 28) facilitated data analysis. Results screened visiting department of psychiatry, FGM inserted eligible both groups which yielded a 196 patient-days (98 98 33). indices CONGA (mg/dl), (76.48 ± 11.9 vs. 65.08 7.12) ( p = 0.048), MAGE (mg/dl) (262.50 25.65 227.54 17.72) 0.012), MODD (18.59 2.77 13.14 2.39) 0.002), MAG(mg/dl) (92.07 6.24vs. 63.86 9.38) <0.001) found significantly higher group. Conclusion Patients more severe depressive symptoms, as suggested by 33, had